Lack of exercise is a causal factor in diseases of civilization and is often associated with physical inactivity, obesity, hypertension, diabetes and lipid disorders. Thus movement is used for prevention and treatment, yet often without detailed knowledge of the reasons for its beneficial effects.
Also in muscular rehabilitation, movement training goes beyond mere muscle effects, requiring a better understanding of how mechanical forces at the molecular, cellular and organ levels are implemented and measured biochemically.
With increasing age, the question is how to stop muscle and bone loss to reduce falls, dependency and other negative quality of life effects.
The core questions of muscle function in health with respect to disease and old age are the plasticity and regenerative capacity, the neural control of movement and questions of energy supply. These are the focal topics of research in this area.