Prof. Dr. Jess Gerrit Snedeker
Prof. Dr. Jess Gerrit Snedeker
Full Professor at the Department of Health Sciences and Technology
Additional information
Research area
The Orthopedic Biomechanics laboratory (headed by Prof. Snedeker) focuses on three primary research areas: mechanical/biological based understanding of tendon disease and healing; micro-mechanical cell-biomaterial interactions and their implications for therapeutic success; and clinical biomechanics for improving existing orthopedic implant design and for the development of novel implants.
Since March 2022 Jess Snedeker has been Full Professor for Orthopedic Biomechanics at ETH Zurich (dual-professorship, University of Zurich).
Education:
- ETH Zurich, Department of Mechanical Engineering, Ph.D. Mechanical Engineering, April 2004
- Pennsylvania State University, College of Engineering, M.Sc. Bioengineering, August 2000
- Lehigh University, College of Engineering and Applied Science, B.Sc. Mechanical Engineering, May 1995
Professional career:
- (2022 – present) Full Professor, ETH Zurich and University of Zurich
- (2020 – present) Vice Chair of Research, Department of Orthopedics, University of Zurich
- (2017 – present) Chief Scientific Officer, Balgrist Campus
- (2011 – 2022) Associate Professor, ETH Zurich and University of Zurich
- (2008 – 2011) Associate Professor, ETH Zurich and University of Zurich
- (2008 – present) Adjunct Faculty, Department of Mechanical Engineering, ETH Zürich
- (2008 – present) Adjunct Faculty, Department of Information Technology and Electrical Engineering, ETH Zürich
- (2006 – 2011) Assistant Professor, University of Zurich, Department of Orthopedics, University Hospital Balgrist, Laboratory for Orthopedic Biomechanics
Additional information
Selected publications:
- G. Fessel, J. G. Snedeker, Evidence against proteoglycan mediated collagen fibril load transmission and dynamic viscoelasticity in tendon. Matrix Biol 28, 503-510 (2009). https://doi.org/10.1016/j.matbio.2009.08.002
- R. I. Sharma, J. G. Snedeker, Biochemical and biomechanical gradients for directed bone marrow stromal cell differentiation toward tendon and bone. Biomaterials 31, 7695-7704 (2010). https://doi.org/10.1016/j.biomaterials.2010.06.046
- Y. Li, G. Fessel, M. Georgiadis, J. G. Snedeker, Advanced glycation end-products diminish tendon collagen fiber sliding. Matrix Biol 32, 169-177 (2013). https://doi.org/10.1016/j.matbio.2013.01.003
- Gautieri et al., Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue. Matrix Biol 59, 95-108 (2017). https://doi.org/10.1016/j.matbio.2016.09.001
- J. Foolen, S. L. Wunderli, S. Loerakker, J. G. Snedeker, Tissue alignment enhances remodeling potential of tendon-derived cells - Lessons from a novel microtissue model of tendon scarring. Matrix Biol 65, 14-29 (2018). https://doi.org/10.1016/j.matbio.2017.06.002
- T. Razafiarison et al., Biomaterial surface energy-driven ligand assembly strongly regulates stem cell mechanosensitivity and fate on very soft substrates. Proc Natl Acad Sci U S A 115, 4631-4636 (2018). https://doi.org/10.1073/pnas.1704543115
- S. L. Wunderli et al., Tendon response to matrix unloading is determined by the patho-physiological niche. Matrix Biol 89, 11-26 (2020). https://doi.org/10.1016/j.matbio.2019.12.003
- A. D. Schoenenberger et al., Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo. Biomaterials 249, 120034 (2020). https://doi.org/10.1016/j.biomaterials.2020.120034
- T. Wang et al., Load-induced regulation of tendon homeostasis by SPARC, a genetic predisposition factor for tendon and ligament injuries. Sci Transl Med 13, (2021). https://doi.org/10.1126/scitranslmed.abe5738
- F. S. Passini et al., Shear-stress sensing by PIEZO1 regulates tendon stiffness in rodents and influences jumping performance in humans. Nat Biomed Eng, (2021). https://doi.org/10.1038/s41551-021-00716-x
Course Catalogue
Spring Semester 2024
| Number | Unit |
|---|---|
| 376-0001-00L | Biomechanics I |
| 376-1974-00L | Colloquium in Biomechanics |