Prof. Dr. Denis Burdakov

Weitere Informationen

SELECTED RESEARCH ACHIEVEMENTS:

Tesmer AL, Li X, Bracey E, Schmandt C, Polania R, Peleg-Raibstein D, Burdakov D (2024) Orexin neurons mediate temptation-resistant voluntary exercise. Nature Neuroscience, 27: 1774-1782

Viskaitis P, Tesmer AL, Liu Z, Karnani MM, Arnold M, Donegan D, Bracey E, Grujic N, Patriarchi T, Peleg-Raibstein D, Burdakov D (2024) Orexin neurons track temporal features of blood glucose in behaving mice. Nature Neuroscience, 27: 1299-1308

Li H-T, Viskaitis P, Bracey E, Peleg-Raibstein D, Burdakov D (2024) Transient targeting of hypothalamic orexin neurons alleviates seizures in a mouse model of epilepsy. Nature Communications, 15: 1249

Grujic N, Tesmer A, Bracey E, Peleg-Raibstein D, Burdakov D (2023) Control and coding of pupil size by hypothalamic orexin neurons, Nature Neuroscience, 26(7):1160-1164.

Li H-T, Donegan D, Peleg-Raibstein D, Burdakov D (2022) Hypothalamic deep brain stimulation as a strategy to manage anxiety disorders. PNAS,119(16): 1-9

Viskaitis P, Arnold M, Garau C, Jensen LT, Fugger L, Burdakov D (2022) Ingested non-essential amino acids recruit brain orexin cells to suppress eating in mice. Current Biology,32: 1-10

Concetti C, Peleg-Raibstein D, Burdakov D (2020) Control of fear extinction by hypothalamic MCH neurons. PNAS, 117(36): 22514-22521

Karnani M, Schöne C, Bracey E, Gonzalez J, Viskaitis P, Li H-T, Adamantidis A, Burdakov D (2020) Role of spontaneous and sensory orexin neuron dynamics in rapid locomotion initiation. Progress in Neurobiology, 187: 101771

Kosse C, Burdakov D (2019) Natural hypothalamic circuit dynamics underlying object memorization. Nature Communications, 10(1): 2505

Blomeley C, Garau C, Burdakov D (2018) Accumbal D2 cells orchestrate innate risk-avoidance according to orexin signals. Nature Neuroscience, 21(1): 29-32

Kosse C, Schöne C, Bracey E, Burdakov D (2017) Orexin-driven GAD65 network of the lateral hypothalamus sets physical activity in mice. PNAS, 114(17): 4525-4530

Gonzalez A, Iordanidou P, Strom M, Adamantidis A, Burdakov D (2016) Awake dynamics and brain-wide inputs of hypothalamic MCH and orexin networks. Nature Communications,7: 11395

Gonzalez A, Jensen L, Iordanidou P, Strom M, Fugger L, Burdakov D (2016) Inhibitory interplay between orexin neurons and eating. Current Biology, 26: 2486-2491

Schöne C, Apergis-Schoute J, Sakurai T, Adamantidis A, Burdakov D (2014) Co-released orexin and glutamate evoked non-redundant spike outputs and computations in histamine neurons. Cell Reports, 7: 697-704

Karnani M, Apergis-Schoute J, Adamantidis A, Jensen L, de Lecea L, Fugger L, Burdakov D (2011) Activation of central orexin/hypocretin neurons by dietary amino acids. Neuron, 74(2): 616-629

Williams RH, Alexopoulos H, Jensen LT, Fugger L, Burdakov D (2008) Adaptive sugar sensors in hypothalamic feeding circuits. PNAS, 105(33): 11975-11980

Gonzalez JA, Jensen LT, Fugger L, Burdakov (2008) Metabolism-independent sugar sensing in central orexin neurons. Diabetes 57(10): 2569-2576

Williams RH, Jensen LT, Vekhratsky A, Fugger L, Burdakov D (2007) Control of hypothalamic orexin neurons by acid and CO2. PNAS, 104(25): 10685-10690